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KMID : 1094020170340060445
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Journal of Veterinary Clinics
2017 Volume.34 No. 6 p.445 ~ p.448
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Clinical Application of Imatinib Mesylate in a Case of Feline Cutaneous Mast Cell Tumor - Clinical Progress, Histopathological, and Immunohistochemical Findings
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Jang Hyo-Mi
Song Joong-Hyun
Hwang Tae-Sung
Lee Hee-Chun
Yu Do-Hyeon
Sur Jung-Hyang
Kang Byeong-Teck
Jo Yang-Rae
Jung Dong-In
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Abstract
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A 1.5-year-old neutered male domestic short hair cat was presented with multiple nodular mass, and suspected mast cell tumor on the surface of the right ear, accompanied by submandibular lymph node involvement. Histopathological Examinations and KIT (CD117) immunohistochemical staining was performed after the surgical resection of the entire right ear pinna. This patient was diagnosed with an anaplastic mast cell tumor with a diffuse positive cytoplasmic expression of KIT. Imatinib mesylate was prescribed after surgical resection; the patient presented without recurrence or metastasis for 2 years. Mild leukopenia was observed as the only side effect of imatinib mesylate during medication.
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KEYWORD
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cat, imatinib mesylate, immunohistochemistry, KIT, mast cell tumor
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